Triclocarban CAS#101-20-2

Triclocarban is a halogenated aromatic compound with potent antimicrobial activity, widely recognized for its use as an effective agent against a broad range of bacteria. Chemically described as 4,4′-(2,3-dichlorophenyl)bis(4-chlorocarbanilide), Triclocarban is known for its ability to inhibit bacterial cell wall synthesis, leading to cell death and preventing the growth of microbes.

This compound has been traditionally used in a variety of applications, including cosmetics, personal care products, and healthcare settings, due to its ability to provide long-lasting antibacterial effects. Triclocarban forms a stable, colorless solution in water and is valued for its compatibility with various formulations, offering a non-irritating and persistent method of microbial control.

However, due to concerns regarding its environmental persistence and potential health effects, regulatory bodies have re-evaluated its use, leading to restrictions or bans in certain applications. Despite these concerns, Triclocarban remains an important compound in the study of antimicrobial agents and their impact on public health and the environment.

In summary, Triclocarban is a historically significant antimicrobial chemical, once widely utilized for its efficacy in preventing bacterial growth

Triclocarban Chemical Properties
Melting point 254-256 °C (lit.)
Boiling point 344.2±42.0 °C(Predicted)
density 1.5732 (rough estimate)
vapor pressure <0.1 mm Hg ( 25 °C)
refractive index 1.6300 (estimate)
Fp 150 °C
storage temp. Sealed in dry,Room Temperature
solubility methanol: soluble
pka 12.77±0.70(Predicted)
form Solid
color Fine plates
Water Solubility <0.1 g/100 mL at 26 ºC
Merck 14,9654
Stability: Stable. Combustible. Incompatible with strong oxidizing agents strong bases.
InChIKey ICUTUKXCWQYESQ-UHFFFAOYSA-N
LogP 3.633 at 25℃
CAS DataBase Reference 101-20-2(CAS DataBase Reference)
NIST Chemistry Reference 3,4,4′-Trichloro carbanilide(101-20-2)
EPA Substance Registry System Triclocarban (101-20-2)
Safety Information
Hazard Codes N
Risk Statements 50/53
Safety Statements 60-61
RIDADR UN 3077 9/PG 3
WGK Germany 2
RTECS FE1250000
HazardClass 9
PackingGroup III
HS Code 38220090
Hazardous Substances Data 101-20-2(Hazardous Substances Data)
Toxicity LD50 ipr-mus: 2100 mg/kg LPPTAK 27,306,79