Isothiazolinones CAS#26172-55-4

Isothiazolinones are a class of broad-spectrum, highly effective fungicides and biocides, composed of 5-chloro-2-methyl-4-thiazoline-3-one (CMI) and 2-methyl-4-thiazoline-3-one (MI). These compounds are recognized for their rapid action against microbes, inhibiting their growth upon contact and leading to cell death 9. They are characterized by high biocidal efficiency, good degradation, no residual, safe operation, compatibility, stabilization, and low operational costs 9.

Isothiazolinones are used in various industrial applications, including cooling water systems and wastewater treatment in fields such as oil, papermaking, pesticides, cutting oils, leather, detergents, and cosmetics. They are compatible with chlorine and most cationic, anionic, and non-ionic surfactants, and at higher dosages, they exhibit excellent bio-sludge stripping effects 9.

The active content in Isothiazolinones-based products typically ranges from 1.5% to 15%, with a pH value between 1.0 and 5.0, depending on the grade. They are available in various forms such as transparent liquids and are packaged in quantities that can be tailored to specific industrial needs 10. Safety precautions are essential when handling Isothiazolinones due to their corrosive nature; they should not come into contact with skin or eyes, and protective equipment is recommended during use

Isothiazolinones Chemical Properties
Melting point 42-45?C
Boiling point 109.7°C
density 1.25 (14% aq.)
refractive index n20/D 1.378
storage temp. Refrigerator
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
form Liquid
pka -4.06±0.40(Predicted)
Stability: Stable. Incompatible with strong oxidizing agents.
LogP 0.240 (est)
CAS DataBase Reference 26172-55-4(CAS DataBase Reference)
NIST Chemistry Reference 5-Chloro-2-methyl-3(2h)-isothiazolone(26172-55-4)
EPA Substance Registry System 5-Chloro-2-methyl-4-isothiazolin-3-one (26172-55-4)
Safety Information
Hazard Codes C,N,T,Xn
Risk Statements 34-43-50-20/21/22-50/53-23/24/25-42/43
Safety Statements 26-36/37/39-45-60-61-24-28-36/37-23
RIDADR UN 1760 8/PG 2
WGK Germany 1
RTECS NX8156850
HazardClass 8
PackingGroup III
HS Code 3808929090
Hazardous Substances Data 26172-55-4(Hazardous Substances Data)