Huperzine A CAS#102518-79-6

Huperzine A is received from Huperzia serrata, which is the perennial fern. It suggests things to do in antipyretic, hemostasis, and dehumidification and is used for the therapy in folks of pneumonia, lung abscess, hematemesis, hematochezia, annoying injury, etc.
Huperzine A is a doable therapeutic agent for Alzheimer ailment that reversible alkaloid inhibitor of AChE which crosses the blood-brain barrier. It reduces mobilephone loss of life brought on with the aid of glutamate in foremost cultures derived from forebrain, hippocampus, cortex and cere.
In China, it is permitted for use in the remedy of Alzheimer’s ailment (AD). Huperzine A was once labeled as a dietary complement through the FDA in 1997. As a nutraceutical, it is accessible in American fitness meals shops or by means of the Internet, labeled as a reminiscence aid.

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Huperzine A CAS#102518-79-6

Product Name: (-)-Huperzine A
Synonyms: Huperzine-A1-5%;(5r-(5-alpha,9-beta,11e))-ydro-7-methyl;5,9-methanocycloocta(b)pyridin-2(1h)-one,5-amino-11-ethylidene-5,6,9,10-tetrah;HUPERIZINE;(-)-HUPERZINE A FROM HUPERZIA SERRATA;HuperziaSerrateP.E120786-18-7/;(5R,9R,E)-5-AMino-11-ethylidene-7-Methyl-5,6,9,10-tetrahydro-5,9-Methanocycloocta[b]pyridin-2(1H)-one;(-)-Huperzine A (HupA)
CAS: 102518-79-6
MF: C15H18N2O
MW: 242.32
EINECS: 600-320-6
Product Categories: Inhibitor;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Alkaloids;API;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Acetylcholine receptor;Nutritional Ingredients;reference substance;102518-79-6
Mol File: 102518-79-6.mol
(-)-Huperzine A Structure
(-)-Huperzine A Chemical Properties
Melting point 211-216oC
alpha D -147° (c = 0.36 in CH3OH) (Ayer); D24.5 -150.4° (c = 0.498 in MeOH) (Liu)
Boiling point 505.0±50.0 °C(Predicted)
density 1.20±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,2-8°C
solubility insoluble in H2O; ≥12.12 mg/mL in DMSO; ≥23.13 mg/mL in EtOH
pka 12.25±0.60(Predicted)
form Solid
color White to Almost white
optical activity [α]/D -153±5°, c = 0.5 in methanol
InChI InChI=1S/C15H18N2O/c1-3-11-10-6-9(2)8-15(11,16)12-4-5-14(18)17-13(12)7-10/h3-6,10H,7-8,16H2,1-2H3,(H,17,18)/b11-3+/t10-,15+/m0/s1
InChIKey ZRJBHWIHUMBLCN-YQEJDHNASA-N
SMILES C12C[C@@]3([H])/C(=C\C)/[C@@](N)(C=1C=CC(=O)N2)CC(C)=C3
LogP 0.833 (est)
CAS DataBase Reference 102518-79-6(CAS DataBase Reference)