Avobenzone CAS #70356-09-1

Avobenzone is a sunscreen agent that protects against the full spectrum of UV light. Of all sunscreen agents, avobenzone has one of the largest absorbance spectrums, absorbing light between 320 – 400 nm (peak absorption ~ 360 nm). Exposure to UV rays is a leading cause of skin cancer, and so use of an effective sunscreen, like avobenzone or avobenzone in combination with other agents, helps to lower risk of developing skin cancer. Avobenzone is specifically the most effective sunscreen agent against UVA rays. Avobenzone is susceptible to photodegredation, and therefore it is important that avobenzone be combined with photostabilizers in the final sunscreen product. It’s been considered a relatively safe chemical, but recent research suggests otherwise. Avobenzone degrades in the sun, resulting in the release of free radicals that may actually increase the risk for cancer.

Avobenzone CAS #70356-09-1

Avobenzone Basic information
Overview Application Properties Toxicity References
Product Name: Avobenzone
Synonyms: AVOBENZONE;EUSOLEX(R) 9020;4-tert-butyl-4′-methoxy-dibenzoylmethane;4-T-BUTYL-4′-METHOXY-DIBENZOYLMETHANE;1-(4-(1,1-Dimethylethyl)phenyl)-3-(4-methoxyphenyl)-1,3-propanedione;1-(4-TERT-BUTYLPHENYL)-3-(4-METHOXYPHENYL) 1,3-PROPANEDIOL;1-(P-T-BUTYLPHENYL)-3-(P-METHOXYPHENYL)-1,3-PROPANEDIONE;1-[4-(1,1-dimethylethyl)phenyl]-3-(4-methoxyphenyl)-3-propanedione
CAS: 70356-09-1
MF: C20H22O3
MW: 310.39
EINECS: 274-581-6
Product Categories: API;Pharmaceutical intermediates;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;cosmetic raw material;UV-Absorber;Organics;70356-09-1
Mol File: 70356-09-1.mol
Avobenzone Structure
Avobenzone Chemical Properties
Melting point 81-84 °C
Boiling point 463.6±35.0 °C(Predicted)
density 1.079
vapor pressure 0Pa at 25℃
storage temp. Inert atmosphere,Room Temperature
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
form Solid
pka 9.74±0.13(Predicted)
color White to Pale Yellow
Water Solubility 27μg/L at 20℃
λmax 356nm(EtOH)(lit.)
Merck 14,888
InChIKey GTIRDWBOUTYFQO-UHFFFAOYSA-N
LogP 6.1 at 20℃
CAS DataBase Reference 70356-09-1(CAS DataBase Reference)
EPA Substance Registry System 1,3-Propanedione, 1-[4-(1,1-dimethylethyl)phenyl]-3-(4-methoxyphenyl)- (70356-09-1)