Polyhexamethylene Biguanide Hydrochloride CAS #32289-58-0

Polyhexanide (Polyhexamethylene biguanide hydrochloride, PHMB) is a polymer used as a disinfectant and antiseptic. Spelled Polihexanide (inn) for dermatological purposes and sold under the names lavasept, serasept, prontosan and omniside. PHMB has been shown to be resistant to Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli, Yeast infection albicans, Aspergillus Brazil, Enterococcus as well as Klebsiella pneumoniae.

The average molecular weight of polyhexamethylene biguanide hydrochloride is 1100-1800, the molecular formula is (C8H17N5)n·xHCl, n=12-16. Polyhexamethylene biguanide hydrochloride (PHMB) is a broad-spectrum antibiotic that can kill gram-positive bacteria, gram-negative bacteria, fungi and yeast.